Sebastian Bauer

Prof. Dr. Sebastian Bauer is a leading oncologist and academic researcher at the University of Duisburg-Essen, affiliated with the Medical Faculty and the West German Cancer Center (WTZ) at University Hospital Essen. He leads the Translational Sarcoma Research group, focusing on soft-tissue sarcomas, particularly gastrointestinal stromal tumors (GIST). His work integrates molecular oncology, preclinical modeling, and clinical trials to advance targeted therapies.

Research Interests: His research spans translational cancer research, oncogenetic signaling pathways, tyrosine kinase inhibitors, preclinical cancer models, and drug development. He investigates mechanisms of resistance in GIST and evaluates novel therapeutic agents in clinical settings.

The recent publication trends highlight a strong focus on targeted therapies (e.g., avapritinib, ripretinib), biomarker discovery (ctDNA, neoantigens), and combination therapies in sarcomas. His work frequently appears in high-impact journals such as Nature Communications and Clinical Cancer Research, reflecting significant contributions to clinical oncology and molecular therapeutics.

Scientific Awards:

• No specific awards mentioned in the provided text.

Advising and Grants: While specific student names are not listed, Prof. Bauer leads a research group and participates in PhD programs through the ZMB (Center for Molecular Biomedicine), indicating active mentoring. His research is supported by national and international collaborations, including DFG, EU programs, and industry partnerships, particularly in drug licensing and clinical trials.

Labs and Teams: He heads the Translational Sarcoma Research group at WTZ Essen, collaborating closely with institutions like TU Dortmund and the Max Planck Institute. His team works on drug discovery, proteogenomics, and clinical trial design, contributing to the development of novel therapies for rare cancers.