Sean Pinney

Sean Pinney is a Professor in the Department of Medicine-Cardiology at the University of Chicago. His research focuses on advanced heart failure, mechanical circulatory support (including LVADs), heart transplantation, and the management of complex cardiovascular conditions. He has been actively involved in clinical trials and translational research, particularly in optimizing therapies for patients with end-stage heart failure.

Dr. Pinney's work spans multiple areas, including the reversal of frailty in patients with ventricular assist devices, immunosuppression strategies post-transplant, and the role of SGLT2 inhibitors in cardiac amyloidosis. He has co-authored over 200 peer-reviewed publications and serves on editorial boards and guideline committees for leading cardiology journals and professional societies.

His research is supported by grants such as NIH R21AG046703 (2014-2017), focusing on whether ventricular assist devices can reverse frailty in heart failure patients. He collaborates with interdisciplinary teams to advance treatments for complex cardiovascular diseases and improve patient outcomes.

Dr. Pinney has contributed to landmark studies on donor heart selection, heart transplantation metrics, and the emergency management of ventricular assist device patients. His clinical expertise is complemented by a focus on health equity in transplant systems and innovative therapies for refractory heart failure.