Sean Conner

Sean Conner is an Associate Professor in the Department of Genetics, Cell Biology, and Development within the College of Biological Sciences at the University of Minnesota. His research focuses on cellular mechanisms of endocytosis, membrane dynamics, and Notch signaling pathways, with implications for understanding cancer metastasis and neurodegenerative diseases.

Dr. Conner's research interests center on understanding the molecular mechanisms of intracellular transport, particularly focusing on endocytosis and membrane dynamics. His work investigates how protein kinases like AAK1 regulate clathrin-mediated endocytosis, Notch signaling pathways, and receptor internalization. His research spans from fundamental cellular processes to implications in cancer metastasis and neurological disorders, with particular emphasis on protein motifs that govern cellular transport mechanisms.

Analysis of Dr. Conner's publication record reveals a consistent research trajectory focused on endocytic mechanisms and membrane dynamics, with increasing emphasis on Notch signaling pathways and their regulation through intracellular transport. His work demonstrates how specific protein kinases control cellular processes with direct relevance to disease mechanisms, particularly in cancer progression and neurodegeneration.

Dr. Conner leads an active research laboratory that employs a multidisciplinary approach combining molecular biology, cell culture techniques, advanced imaging, and biochemical analyses. His laboratory has made significant contributions to understanding the role of specific protein motifs in receptor internalization, the regulation of Notch signaling through intracellular transport, and the mechanisms of membrane protein recycling, with research funding supporting investigations into both basic science and potential therapeutic applications.