Sarah Dick

Dr. Sarah Dick is an Assistant Professor in the Department of Biomedical and Molecular Sciences at Queen’s University’s School of Medicine, Faculty of Health Sciences. Her research focuses on understanding cellular interactions, intracellular signaling, and tissue niche factors in cardiovascular health and disease. She employs mouse models of ischemic injury, genetic fate mapping, and single-cell RNA-sequencing to study macrophage heterogeneity in the heart and their roles in regeneration.

Dr. Dick’s research interests span human endocrinology, nutrient signaling, and cell signaling pathways. She investigates how resident macrophage subsets expand to mediate protective and regenerative functions following cardiac injury. Her work aims to improve cardiovascular outcomes through insights into tissue immunology and inflammation.

Selected articles highlight her contributions to macrophage biology, including studies on tissue-specific macrophage subsets, IGF-1’s role in cardiac growth, and radiation’s impact on atherosclerosis. Her research integrates molecular, cellular, and systems biology approaches to address fundamental questions in regenerative medicine and chronic disease.