About
Sara Bohman is a Senior Lecturer in Anatomy at the Department of Medical Cell Biology, Faculty of Medicine, Uppsala University, serving as study director and course leader for anatomy in the Medical Program and Biomedicine Program.
Her research centers on diabetes pathophysiology and pancreatic islet transplantation, with emphasis on amyloid formation mechanisms in transplanted islets, microencapsulation techniques for immunoisolation, and functional outcomes of grafts. She investigates how blood perfusion patterns influence amyloid deposition and evaluates biomaterials like barium-alginate microcapsules to overcome immune rejection challenges in type 2 diabetes treatment.
Her publication timeline (2006-2017) reveals consistent focus on islet transplantation barriers, particularly amyloid-induced graft failure and suboptimal outcomes of encapsulation methods. Key contributions include demonstrating preferential amyloid deposition in highly functional islets, showing limited efficacy of microencapsulation at subcutaneous sites, and analyzing alpha cell preservation in transplants. Her work bridges cell biology and clinical diabetes research through experimental models of non-vascularized grafts.
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