Sara Badodi

Dr. Sara Badodi serves as Senior Lecturer in Paediatric Brain Tumour Epigenetics at the Centre for Genomics and Child Health within the Blizard Institute, Queen Mary University of London's Faculty of Medicine and Dentistry. Her work focuses on epigenetic mechanisms driving childhood brain cancers, the leading cause of tumor-related death in children.

Education

• PhD in Molecular and Regenerative Medicine, University of Modena and Reggio Emilia, Italy (research on childhood rhabdomyosarcoma)

Research Focus

Dr. Badodi investigates epigenetic dysregulation in paediatric brain tumours, particularly medulloblastoma, to develop molecularly-tailored therapies with reduced side effects. Her lab explores how epigenetic modifications interact with metabolic pathways to drive tumor progression, utilizing patient-derived models and molecular techniques to identify novel therapeutic targets.

Publication Trends

Her 2017-2022 publications reveal consistent focus on medulloblastoma epigenetics, with key themes including BMI1/ERK signaling convergence, metabolic adaptation mechanisms, and therapeutic interventions like inositol treatment. The work bridges basic epigenetic research with translational applications, emphasizing combinatorial drug approaches and patient-derived model systems.

Scientific Awards

No specific awards or fellowships were documented in the provided materials.

Advising and Funding

• Supervises PhD students: Alexandra Hadaway and Thomas Willott
• Offers lab experience placements for prospective researchers
• Research fellowship previously funded by Brain Tumour Research

Research Team

Leads a dedicated group within the Centre for Genomics and Child Health, currently including researcher Jessica Sohl. The team specializes in epigenetic profiling, metabolic adaptation studies, and therapeutic testing using primary medulloblastoma cell lines.