Sambriddhi Mainali

Sambriddhi Mainali serves as the Undergraduate Programs Director and Assistant Teaching Professor in the Department of Computer Science at the University of Missouri-St. Louis within the College of Arts and Sciences. Holding a Ph.D. in Computer Science from the University of Memphis (2021), she bridges computational theory with biological applications through her research and teaching.

Education:

• Ph.D. in Computer Science, University of Memphis, 2021

Dr. Mainali's research program focuses on computational biology and bioinformatics, employing advanced machine learning, information theory, and molecular computing techniques to solve genomic challenges. Her work spans pathogenicity prediction, genomic sequence analysis, phenotype forecasting, and environmental DNA profiling, with particular emphasis on dimensionality reduction methods and species identification systems. This interdisciplinary approach integrates computer science fundamentals with biological data to advance precision medicine and biodiversity conservation.

Analysis of her 14 publications from 2017-2022 reveals consistent innovation in genomic data science, with recent work emphasizing deep learning for DNA structure analysis (2022), information-theoretic dimensionality reduction (2021), and universal genomic positioning systems (2017-2020). Her research trajectory demonstrates increasing sophistication in applying computational frameworks to complex biological questions, particularly in translating genomic sequences into phenotypic predictions and environmental assessments.

As Undergraduate Programs Director, she oversees curriculum development and student mentorship in computer science, maintaining office hours Tuesdays and Wednesdays 1:30-3:30 PM in ESH 313 with Zoom availability. Her contact details include email smbtk@umsl.edu and phone (314) 516-5239.