Sally Temple
Research Professor · Neural stem cell research
Icahn School of Medicine at Mount SinaiAbout
Dr. Sally Temple is a Research Professor and Scientific Director of the Neural Stem Cell Institute. She discovered neural stem cells in the embryonic mammalian brain and leads a team of 30 researchers focused on therapies for CNS disorders. A Cambridge and UCL-trained developmental biologist and neuroscientist, she co-founded NSCI and serves on the board of the International Society for Stem Cell Research.
- MacArthur Fellowship Award (2008)
Her research spans neural stem cell characterization, CNS repair mechanisms, and translational applications for eye/brain/spinal cord disorders. Key themes include:
- Neural stem cell niche regulation
- Shh signaling in spinal cord recovery
- iPSC models for neurodegenerative diseases
- RPE stem cell activation for regeneration
- Transcriptomic analysis of cerebral cortex development
Her work has produced groundbreaking insights into asymmetric cell division, environmental sensing, and therapeutic delivery systems. Publications highlight collaborations with leading researchers in stem cell biology and regenerative medicine.
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