Sabine Amslinger

Sabine Amslinger is a researcher at the Institute of Organic Chemistry, University of Regensburg, focusing on bioorganic and medicinal chemistry. Her work spans natural product synthesis, anti-inflammatory drug development, and mechanism exploration via HO-1 induction.

Education: Studied Chemistry at Friedrich-Alexander University Erlangen-Nürnberg (Germany) and the University of Lawrence (Kansas, USA), completing her diploma thesis on biotinylated glycolipids. Earned her PhD in terpene biosynthesis at Technical University Munich under Prof. Dr. Dr. A. Bacher (2000-2003). Conducted postdoctoral research at University of California, Berkeley (2004-2006) under Prof. Dr. K. P. C. Vollhardt.

Research Interests: Centered on bioorganic chemistry and medicinal applications, specifically synthesizing and evaluating natural products as potential drugs. Key focus areas include anti-inflammatory agents, HO-1 stimulation, and chalcone derivatives for immunomodulation. Her synthetic strategies involve cobalt-mediated cyclizations and Michael acceptor tuning.

Publications: Recent articles highlight the role of HO-1 inducers in cytoprotection, chalcone derivatives as JAK/STAT inhibitors, and click chemistry for target identification in natural products like xanthohumol. These span organic synthesis, pharmacology, and immunology.