Ryan Jason Schmidt

Ryan Jason Schmidt, MD, PhD, is an Assistant Professor of Clinical Pathology at the University of Southern California. His research focuses on genomic diagnostics, molecular pathology, and clinical bioinformatics, with a particular emphasis on pediatric genetics and oncology. He has contributed to developing standards for clinical bioinformatics practice and improving diagnostic workflows through genomic analysis.

His work spans genomic characterization of pediatric cancers, gene fusion detection in tumors, and the integration of epigenetic markers in tumor diagnosis. He has co-authored guidelines on variant classification, risk allele reporting, and next-generation sequencing validation in collaboration with professional societies.

Dr. Schmidt's recent studies highlight advancements in optical genome mapping, copy number variant analysis, and transcriptome sequencing applications in clinical settings. His publications emphasize precision medicine applications and ethical considerations in gene editing for pathologists.

He holds a leadership role in the Association for Molecular Pathology's Clinical Bioinformatician Body of Knowledge project and has developed educational initiatives for clinical pathology residents in reference laboratory settings.