Ruby Law

Ruby Law is an Associate Professor (Research) in Biochemistry & Molecular Biology at Monash University, affiliated with the Monash Biomedicine Discovery Institute and Victorian Heart Institute (VHI). She specializes in structural biology, focusing on protein structure-function relationships in health and disease. Her work includes studies on the fibrinolytic system, pore-forming proteins, and glutamic acid decarboxylase (GAD), employing techniques like X-ray crystallography, cryo-electron microscopy, and small-angle X-ray scattering.

Education: PhD and postdoc in yeast mitochondrial bioenergetics at Monash University. Postdoctoral research included translational studies at Autogen Biotech and work on liver fluke proteases at the Molecular Parasitology group. Since 2002, she has been part of the Structural Biology Group, leading research on human protein structures.

Research Interests: Regulation of proteases in fibrinolysis, pore-forming proteins in immunity, and GAD dysfunction in neurological disorders. Current projects include developing perforin inhibitors for bone marrow transplants and optimizing XFEL-based structural studies. She also co-founded the Monash Human Monoclonal Antibody Library Group.

Grants & Collaborations: Lead investigator on NHMRC-funded projects studying plasminogen and GAD. Collaborates with medicinal chemists and single-molecule microscopy experts on drug discovery. Active in international workshops on structural biology techniques.

Mentorship: Provides training for female migrant scientists and has mentored over six individuals in the past decade. Focuses on career development and laboratory skills.