Ross Chapman

J. Ross Chapman is a Professor of Genome Maintenance Biology at the University of Oxford, affiliated with the MRC Molecular Haematology Unit. He holds fellowships from Cancer Research UK and the Lister Institute, and is part of the EMBO Young Investigator Programme. His research focuses on DNA repair mechanisms, particularly the balance between accurate and mutagenic repair pathways in cancer and immune disorders.

Career highlights include roles as a Sir Henry Wellcome Fellow and Principal Investigator. His group studies genetic recombination mechanisms, aiming to develop cancer therapies targeting repair pathway dysfunctions. Key research areas include the role of BRCA1, BARD1, 53BP1, and CST complexes in DNA repair.

Awards include CRUK and Lister Institute Fellowships, alongside EMBO recognition. His lab’s work spans genomic stability, immune system development, and cancer therapy strategies. Recent studies explore chronic inflammation in leukemia evolution and synthetic lethality in BRCA-deficient cells.