Robert Prins
Associate Professor · Tumor Immunology
University of California, Los AngelesAbout
Robert Prins is an Associate Professor at the David Geffen School of Medicine, University of California, Los Angeles (UCLA), with dual appointments in the Departments of Neurosurgery and Molecular & Medical Pharmacology. His research focuses on immune-based therapies for central nervous system (CNS) tumors, particularly glioblastoma, bridging preclinical models with clinical immunotherapy trials.
- Joint faculty appointments in Neurosurgery and Molecular & Medical Pharmacology
- Director of the I3T Seminar Series and Brain Tumor Immunology Research Lab
- Active in clinical trials for brain tumor immunotherapy
Prins' work emphasizes understanding tumor immunology and developing novel immune-based treatments. His laboratory investigates mechanisms of T-cell activation, tumor immune evasion, and strategies to overcome immunosuppression in brain tumors. He has contributed extensively to studies on dendritic cell vaccination, checkpoint inhibitors, and metabolic tumor characterization using advanced imaging.
Recent research highlights include:
- 2025 studies on NY-ESO-1 targeting in meningiomas
- 2024 analyses of ERK phosphorylation as a biomarker in glioblastoma
- 2023-2025 investigations into diffusion MRI phenotypes and immune checkpoint blockade effects
- 2022-2024 work on immunotherapy resistance mechanisms in CNS tumors
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