Robert Kratzke

Robert Kratzke, MD, is a Professor of Medicine and Section Head of Medical Oncology at the University of Minnesota, specializing in the Division of Hematology, Oncology, and Transplantation. His research focuses on lung cancer and mesothelioma, with emphasis on immunotherapy, virotherapy, and biomarker development.

• Key Research Areas: Targeted therapies for KRAS mutations, ADAR1 regulation in tumorigenesis, microbiota modulation in NSCLC, and VISTA immune checkpoint inhibition.
• Clinical Trials: Participated in phase II trials for microbiota therapy in metastatic NSCLC and maintenance pemetrexed for mesothelioma.

Scientific Trends: Recent publications highlight RNA editing (ADAR1), splicing factors (SFPQ), and translational control in thoracic malignancies. His work bridges genetic profiling, virotherapy, and novel drug sensitization strategies.

Grants & Collaborations: Active in CALGB/Alliance trials, exploring tumor mutation burden, chemotherapy pharmacogenomics, and oncolytic virus delivery systems.