Richard Wade-Martins

Professor Richard Wade-Martins is a leading academic in University of Oxford's Department of Physiology, Anatomy and Genetics. He directs the Molecular Neurodegeneration Research Laboratory and the Oxford Parkinson’s Disease Centre (OPDC). With degrees from Cambridge (MA) and Oxford (DPhil), he has held prestigious fellowships including Wellcome Trust Research Career Development Fellowship and NIH reviewer roles.

His research targets molecular mechanisms in Parkinson’s and Alzheimer’s diseases through iPSC models, transgenic mice, and lysosomal function studies. He pioneered work on SNCA, MAPT, and LRRK2 gene pathways. Current projects focus on gene therapy and mitochondrial dysfunction in neurodegeneration.

Key publications (2019–2025) reveal trends in single-cell transcriptomics, calcium channel inhibition, and TFEB/TFE3 lysosome modulation. His awards include Wellcome Trust Fellowships and advisory roles for Parkinson's UK, Alzheimer's Research UK, and EU consortia like StemBANCC and EFACTS. He leads the UK Dementia Platform iPSC Initiative and serves on international boards in Luxembourg and Canada.