Richard Monaghan

Richard Monaghan is a Research Fellow at the University of Manchester's Division of Cardiovascular Sciences. His research focuses on cardiovascular and lymphatic developmental disorders, mitochondrial biology, and ageing mechanisms. He holds a PhD from the University of Manchester, supervised by Prof. Whitmarsh. His work contributes to UN Sustainable Development Goals related to health and well-being.

• Roles: Research Fellow (Division of Cardiovascular Sciences)
• Education: PhD in Mitochondrial Biology (University of Manchester, 2012)

His research interests span mitochondrial-endoplasmic reticulum interactions, genetic contributors to congenital heart defects like Tetralogy of Fallot, and the molecular mechanisms underlying ageing and healthspan. Recent work includes investigating FLT4's role in cardiovascular/lymphatic disorders and therapeutic targets for mitochondrial contact sites.

Grants:

• Lead contributor: 'Investigation of genetic mechanisms underlying congenital heart disease' (2021-2026)
• Contributor: 'Novel ageing-related ROS homeostasis pathway' (2012-2015)

Key Research Themes:

• Cardiovascular and lymphatic system development
• Mitochondrial biology and cellular stress responses
• Genetic basis of congenital defects
• Ageing mechanisms and healthspan regulation

His research has been disseminated through 18 peer-reviewed articles, including high-impact contributions to Open Biology and Cardiovascular Research.