About
Dr. Richard Killick is a Lecturer in Psychological Medicine at King's College London, specializing in neurodegenerative diseases, particularly Alzheimer's and Parkinson's. His research focuses on molecular mechanisms linking amyloid-β, tau pathology, and synaptic dysfunction, with an emphasis on therapeutic interventions targeting Wnt signaling, ROCK inhibitors, and diabetes-AD interactions. He leads projects on biomarker discovery and imaging techniques for assessing Alzheimer's pathology.
Key research interests include synaptic toxicity, tau phosphorylation, and the role of karyopherins in neurodegeneration. Collaborations involve analyzing longitudinal health data to understand disease trajectories, as seen in studies using electronic health records of 57 million adults in England. Killick’s work contributes to UN Sustainable Development Goals related to good health and well-being.
Recent articles highlight innovative approaches like masking amyloid precursor protein and repurposing drugs such as fasudil. His projects, funded by organizations like Alzheimer’s Society and the Rosetrees Trust, aim to identify common disease mechanisms in neurodegenerative conditions and develop imaging tools for treatment monitoring.
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