Raquel Lieberman

Raquel Lieberman is a Professor at the Georgia Institute of Technology, holding the Sepcic-Pfiel Chair in Chemistry. Her lab investigates the molecular mechanisms of protein misfolding and membrane enzymology, with a focus on diseases like glaucoma and Alzheimer's. She can be reached at raquel.lieberman@chemistry.gatech.edu.

• B.Sc., Massachusetts Institute of Technology (1998)
• M.S., Northwestern University (1999)
• Ph.D., Northwestern University (2005)
• Postdoctoral Research Fellow, Harvard Medical School/Brandeis University (2005-2007)

Research Interests:

• Protein misfolding and aggregation in glaucoma (myocilin)
• Intramembrane proteases in neurodegenerative diseases
• Structural and biophysical characterization of membrane enzymes

Scientific Awards:

• PEW Scholar in Biomedical Sciences (2010)
• Blanchard Fellowship (2010)
• Rosalinde & Arthur Gilbert/AFAR New Investigator Award (2009)
• NSF CAREER Award (2008)
• Glaucoma Research Foundation Shaffer Award (2008)
• ACS Nobel Laureate Signature Award for Graduate Education (2006)
• NIH Postdoctoral Fellowship (2005)

The Lieberman lab employs crystallography, neutron scattering, and proteomics to study protein folding and membrane enzymology. They are pioneering pharmacological chaperone discovery for glaucoma therapeutics and structural characterization of intramembrane proteases, with recent work focusing on AI-driven mutation classification and lipid-dependent enzyme oligomerization.