About
Prof. R.J. de Boer is a Professor of Theoretical Biology at Utrecht University, Faculty of Science, Department of Biology. His research focuses on quantitative immunology, using mathematical modeling to study immune system dynamics, host-pathogen interactions, and T-cell behavior. He leads the Theoretical Biology group and collaborates with consortia like EPIICAL.
De Boer's work bridges immunology, computational biology, and evolutionary theory. Key interests include T-cell turnover, HIV dynamics, immune aging, and host-pathogen coevolution. His lab employs techniques like deuterium labeling and in silico modeling to analyze immune responses in health and disease.
Recent publications emphasize T-cell memory, HIV reservoir dynamics, pediatric immunology, and computational methods in immunology. His articles frequently explore viral persistence, immune reconstitution, and the impact of aging on lymphocyte populations.
De Boer contributes to interdisciplinary projects linking biological defense mechanisms to cybersecurity frameworks. He teaches courses in Biological Modeling and Immunobiology, advancing quantitative approaches in life sciences education.



