
About
Pål Falnes is a Professor at the University of Oslo, affiliated with the Department of Biochemistry and Molecular Biology. His research focuses on protein methylation, particularly in mitochondrial contexts and its implications for RNA/DNA repair mechanisms.
- Active in studying seven-β-strand (METTL) methyltransferases and their roles in lysine methylation.
- Investigates mitochondrial enzymatic activity, including ATP synthase and citrate synthase regulation.
Research Interests:
Dr. Falnes specializes in post-translational modifications, particularly lysine and histidine methylation. His work bridges protein-RNA interactions, translation dynamics, and mitochondrial metabolism, with recent studies on METTL family members like METTL13, METTL18, and FAM173B.
Article Trends:
Publications highlight METTL methyltransferases in human proteomics, mitochondrial respiration regulation, and DNA/RNA repair via AlkB proteins. Key themes include chronic pain mechanisms, ribosome biogenesis, and sequence-specific enzymatic methylation.
Research Groups:
He leads the Biological Methylation - Falnes group and contributes to the Center for Computational Inference in Evolutionary Life Science (CELS).
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