Praveen R. Juvvadi

Praveen R. Juvvadi, Ph.D., an Associate Professor, is a leading researcher at Arkansas Children's focusing on invasive fungal infections caused by Aspergillus fumigatus, Candida, and Cryptococcus. His work addresses the rising mortality rate of invasive aspergillosis (IA) in immunocompromised patients due to antifungal resistance.

• Research emphasizes identifying fungal growth and virulence mechanisms using genetic, biochemical, and proteomic techniques
• Key discoveries include calcineurin (CN) as a critical target for antifungal development
• Ongoing work explores CN regulatory networks, structural inhibitor design, and protein kinase A signaling

This research has translational potential for novel therapies against emerging fungal threats.