About
Prajwal Boddu, MD, is an Instructor of Medicine in the Department of Medical Oncology and Hematology at Yale School of Medicine. He holds affiliations with the Janeway Society and Pillai Lab at Yale Cancer Center. His clinical expertise spans hematology and oncology, focusing on blood disorders and malignancies. Dr. Boddu completed his MD at Osmania Medical College (2012), followed by residency at Advocate Illinois Masonic Medical Center (2016) and a hematology fellowship at MD Anderson Cancer Center (2018).
Research Interests: Dr. Boddu’s work centers on RNA-mediated epigenetic reprogramming in clonal myeloid disorders. He investigates transcription elongation defects linked to SF3B1 mutations and their role in chromatin landscape alterations. His studies also explore therapeutic strategies for splicing factor mutant myelodysplastic syndromes (MDS).
Collaborations: Active collaborations include Dr. Manoj Pillai (mentor), Karla Neugebauer, Rory Shallis, and Amer Zeidan, focusing on RNA processing, chromatin dynamics, and transcriptional regulation in hematologic cancers.
Labs & Teams: He is affiliated with the Pillai Lab and participates in interdisciplinary teams at the Janeway Society and Yale Cancer Center, emphasizing translational research in blood cancers.
