Peter Rayner

Peter Rayner is an Associate Lecturer in the Department of Chemistry at the University of York, affiliated with the Centre for Hyperpolarisation in Magnetic Resonance. He holds an MChem (2009) and a PhD in Organic Chemistry (2013), both from the University of York. His research focuses on developing synthetic and catalytic chemistry for biomedical applications, particularly leveraging the SABRE (Signal Amplification by Reversible Exchange) technique to enhance nuclear magnetic resonance (NMR) imaging for diagnostic purposes. Key areas include designing isotopically labeled substrates and novel ligands for SABRE catalysts to improve hyperpolarization and prolong magnetic lifetimes. He has presented at conferences such as the Dalton Division Northern Meeting and the NMR Discussion Group, and his work spans interdisciplinary collaborations in analytical chemistry, catalysis, and materials science.

Rayner’s research emphasizes translating SABRE advancements into pre-clinical MRI applications for disease diagnosis. His publications highlight innovations in catalyst design, hyperpolarization methods, and applications in drug scaffolds, including tuberculosis treatments. Over 30 peer-reviewed articles and seven datasets underscore his contributions to SABRE’s development and its biomedical potential. His lab utilizes techniques like X-ray crystallography and mass spectrometry to study structure-activity relationships, driving advancements in hyperpolarized MRI probes and pharmaceutical agents.