Peter J. Park

Peter J. Park is the BIG Program Director and Professor of Biomedical Informatics at Harvard Medical School. He leads a computational biology group affiliated with the Harvard Ludwig Center, Brain Somatic Mosaicism Network, 4D Nucleome Network, and Brigham and Women’s Hospital.

His research focuses on:

• Genome and epigenome analysis of somatic mutations
• Non-coding mutation roles in disease
• Mosaic mutations in neurodegeneration and cancer
• Single-cell sequencing for low-frequency variant detection

His lab develops computational tools like MuSiCal (mutational signatures), Chromoscope (SV visualization), and MosaicForecast (machine learning variant calling), with applications across cancer biology and neuroscience consortia.