Per Bruheim

Per Bruheim is a Professor at the Department of Biotechnology and Food Science, Norwegian University of Science and Technology (NTNU). He leads the Bruheim research group, focusing on Deep Phenotyping of prokaryotic and eukaryotic systems using advanced metabolomics, fluxomics, and lipidomics techniques. He is the scientific leader of the NV faculty Mass Spectrometry lab and has developed targeted/non-targeted MS methods applied to diverse biological systems.

Teaching roles include leading the 2-year and 5-year Biotechnology programs (MSBIOTECH and MBIOT5). He teaches courses such as TBT4140 Biochemical Engineering, TBT4110 Microbiology, and TKP4170 Process Design. Current research projects include targeting antibiotic resistance via bacterial stress responses (Trond Mohn Foundation), chemically defined cell culture media development, and peptide drug inhibition of translesion synthesis mechanisms.

Research interests center on metabolomics and systems biology approaches to study microbial physiology and antibiotic resistance, with applications in bioprocessing and sustainable protein production. His lab employs mass spectrometry for precise metabolic profiling and collaborates internationally on projects involving lipidomics and flux analysis.

Advising and grants involve mentoring over a dozen master’s theses on topics like microbial fermentation optimization, single-cell protein production, and recombinant protein expression. He actively pursues funding for projects addressing AMR mechanisms and bioprocess innovation. The Bruheim group also collaborates with industry on sustainable raw material utilization for microbial cultures.

Labs/Teams: Leads the Mass Spectrometry facility at NTNU and directs the Bruheim research group within the Institute of Biotechnology (IBT). Collaborates with national/international partners in microbiology, metabolomics, and bioprocessing.