Paula Preston-Hurlburt

Paula Preston-Hurlburt is a Research Associate in Immunobiology at Yale School of Medicine, working in the Herold Lab. Her research focuses on immune mechanisms in type 1 diabetes and transplantation immunology.

She investigates T cell responses in autoimmune conditions, particularly how therapies like teplizumab modulate antigen-specific repertoires in diabetes prevention. Additional work examines RAGE receptor signaling in T cell activation and graft rejection mechanisms in humanized mouse models.

Her collaborative research includes studies of SARS-CoV-2 immune responses across age groups and development of immunotherapies for autoimmune disorders. Recent publications demonstrate expertise in translational immunology with clinical applications.

She contributes to projects funded by NIH and diabetes research foundations, employing cellular immunology techniques and preclinical models.