
About
Paul O’Toole is Professor of Microbial Genomics and Head of the Department of Microbiology at University College Cork (UCC), Ireland. He is a Principal Investigator at APC Microbiome Ireland, a world-leading research center dedicated to understanding the human microbiome in health and disease.
His research focuses on the functional genomics of gastrointestinal bacteria, particularly Lactobacillus genomics and phylogeny, and the role of the gut microbiota in ageing, colorectal cancer, and irritable bowel syndrome (IBS). He leads large-scale national and international projects examining how habitual diet shapes the microbiome and influences disease risk, with the ultimate goal of controlling host-microbiome interactions in multifactorial diseases.
O’Toole’s lab is supported by major funding bodies including Science Foundation Ireland, the Department of Agriculture, Food and the Marine, the Health Research Board, and the European Union. His work integrates genomics, microbiology, and human health to advance precision medicine and microbiome-based therapeutics.
He has a strong publication record and contributes significantly to the global understanding of the gut microbiome. His leadership in APC Microbiome Ireland positions him at the forefront of microbiome research.
Scientific Awards:
- No specific awards listed in the provided text.
Advising and Grants:
O’Toole leads a major research program with sustained funding from national and international agencies. While specific student names are not listed, his role as a Principal Investigator and Professor indicates active supervision of PhD and postgraduate researchers. His grants support interdisciplinary projects on microbiome dynamics in ageing and disease.
Labs and Teams:
He leads a research group within APC Microbiome Ireland, based in the Biosciences Building at UCC. His team conducts cutting-edge research on microbial genomics and host interactions, contributing to one of the most influential microbiome research centers globally.



