Paul M. Mathews

Paul M. Mathews is a Researcher at the New York University in the Grossman School of Medicine, affiliated with the Department of Psychiatry. His work focuses on molecular, cellular, and translational neuroscience, with a particular emphasis on neurodegenerative diseases like Alzheimer's and their underlying cellular mechanisms.

• Education: PhD from Johns Hopkins University

His research explores the role of endosomal pathways, apolipoprotein E alleles, and amyloid precursor protein in neurodegeneration, with publications analyzing synaptic dysfunction, cholinergic neuron loss, and metabolic influences such as Western diets. He also investigates amyloid fragments in brain tissue using advanced imaging techniques.

Recent publications highlight connections between endosomal trafficking, neuroinflammation, and neurodegenerative disease progression. His work spans molecular neuroscience and translational studies, often utilizing mouse models to understand genetic and metabolic factors.

For contact, his email is Paul.Mathews@nyulangone.org.