Paul J. Kammermeier

Paul J. Kammermeier is an Associate Professor in the Department of Pharmacology and Physiology at the University of Rochester Medical Center (School of Medicine and Dentistry). His research focuses on G protein-coupled receptor (GPCR) signaling, particularly metabotropic glutamate receptors (mGluRs) and their role in ion channel modulation and synaptic plasticity.

Key research areas include:

• Receptor dimerization mechanisms (homodimers vs. heterodimers)
• Homer protein scaffolding in postsynaptic signaling
• Calcium channel regulation by accessory subunits
• GPCR signal transduction specificity

His lab employs electrophysiology, molecular biology, and fluorescence imaging to study both primary SCG neurons and native retinal/hippocampal systems. Collaborations include institutions like Johns Hopkins and University of Michigan. Notable honors include election as Councilor of the University of New York Pharmacology Society (2012) and co-editing the textbook Ion Channels: A Laboratory Manual (2017).

His 15 most recent publications highlight trends in:

• GPCR heterodimerization pharmacology
• Calcium signaling in secretory networks
• Homer-Preso1 regulatory pathways
• Evaluating drug selectivity in glutamate receptors
• Quantitative imaging of protein complexes

Current lab members include graduate students Tyler W. McCullock and Tahia Rahman. Former students and postdocs (e.g., Mallory Scott, Donald Beqollari) have contributed to understanding mGluR signaling and ion channel modulation.