About
Dr. Patrick A. Flume is a Professor in the Department of Medicine at the Medical University of South Carolina (MUSC) College of Medicine. He serves as the Powers-Huggins Endowed Chair for Cystic Fibrosis and focuses on patients with cystic fibrosis, bronchiectasis, and non-tuberculous mycobacteria (NTM) lung infections.
- Specializes in chronic infection management
- Expert in medication toxicities and treatment practices
- Leads multidisciplinary teams for pulmonary exacerbation research
- Develops quality improvement frameworks for respiratory care
His work spans clinical trials (e.g., 2021 antibiotic duration study), guideline development (2018 ECFS revisions), and pathophysiological investigations (2025 neutrophil protease targeting). Research emphasizes disease heterogeneity, microbiome interactions, and equitable treatment access.
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