Patricia Roxburgh

Patricia Roxburgh is a Professor of Experimental Cancer Medicine at the University of Glasgow, affiliated with the Clinical Research Garscube. Her research focuses on gynaecological cancers, particularly ovarian and colorectal malignancies, with an emphasis on genomic alterations, targeted therapies, and clinical trial design.

• Education: Not explicitly stated
• Appointments: University of Glasgow, Beatson Cancer Charity, Cancer Research UK

Roxburgh's work spans BRCA mutations, PARP inhibitors, and the role of biomarkers like p53 and CA-125 in treatment response. She explores epigenetic mechanisms, immune modulation, and precision medicine strategies.

The 15 most recent articles highlight her contributions to ovarian cancer genomics (e.g., structural variants, multiomic patient stratification), drug combination studies (PARP inhibitors with immunotherapies, capecitabine with radiotherapy), and biomarker validation (CA-125 as a prognostic indicator, p53 mutation dynamics).

• Grants: Genomic landscape of ovarian cancer (Tenovus Scotland), IMAGINE (Beatson Cancer Charity), PAIRS (Wellbeing of Women), Precision Medicine Laboratory sequencing (Beatson Cancer Charity)
• Current Projects: ECMC QQR, CRUK Centre Renewal, NHS ovarian cancer studies

Roxburgh collaborates with teams at the Institute of Cancer Sciences and participates in clinical trials targeting chemoresistance, immunotherapy, and personalized treatment regimens.