Parijat Sengupta

Parijat Sengupta is an Assistant Research Professor in the Department of Bioengineering at the University of Illinois at Urbana-Champaign (UIUC), affiliated with the Beckman Institute for Advanced Science and Technology. His research focuses on understanding neuronal network signaling in brain trauma and neurodegenerative diseases, using optogenetics, electrophysiology, and advanced imaging techniques. The Sengupta Lab (OpNTech) develops in vitro models to study neuronal equilibrium dynamics under mechanical and chemical perturbations. His work has been featured in high-impact journals like Nature Physics and collaborations with institutions such as LIBNA and Prof. Stephen Boppart’s team.

Education details are listed in professional profiles but not explicitly detailed here. His research integrates interdisciplinary approaches to probe neural networks with tools like multi-electrode electrophysiology (MEE), fluorescence correlation spectroscopy (FCS), and calcium imaging. Key areas include optogenetic stimulation, quantum coherence in biological systems, and the development of bio-bots using optogenetic skeletal muscle control.

Notable contributions include demonstrating quantum coherent control of neurons, published in Nature Physics, and collaborative work on bio-bots using optogenetic stimulation. His lab advises students across disciplines, including Kimberly Sam (Fulbright Scholar), Nainika Roy, Gelson Pagán Díaz, and Carlos Renteria. The lab also emphasizes training through programs like the Microbiology Summer Research Program and Undergraduate Research Week Symposium.

OpNTech’s current work spans neural circuit analysis, traumatic brain injury models, and the development of platforms like OptoMEA for neuronal signaling efficiency. Future directions include advancing optogenetic tools and exploring neuroimmune interactions in sleep regulation.