About
Paolo Decuzzi is a Senior Researcher and the Founding Director of the Laboratory of Nanotechnology for Precision Medicine at the Italian Institute of Technology in Genova, Italy. With a distinguished career spanning multiple continents, he has established himself as a leader in nanomedicine research.
His educational background includes an M.Sc. and Ph.D. in Mechanical Engineering from Italian institutions, followed by academic appointments at Polytechnic University of Bari, University 'Magna Graecia' of Catanzaro, University of Texas Health Science Center, and Houston Methodist Hospital before joining IIT Genova in 2015. His international experience includes visiting positions at Stanford Medicine, Princeton, Ohio State University, and the University of Michigan.
Dr. Decuzzi's research focuses on applying engineering principles to medical challenges through nanotechnology. His laboratory specializes in designing multifunctional nanoconstructs for precision drug delivery, with applications in brain cancer therapy, neurodevelopmental disorders, diabetes management, and immunotherapy. His approach emphasizes the rational design of nanoscale systems that can navigate biological barriers to deliver therapeutics precisely where needed.
His recent publications (2024) demonstrate continued innovation in developing microparticles for neuroinflammation, protein nanoaggregates for immune activation, microplate systems for insulin delivery, and advanced polymeric implants with controlled release properties. These works reflect his lab's commitment to addressing diverse medical challenges through engineered nanoscale solutions.
- European Research Council Consolidator Grant (2014)
- President of Controlled Release Society Italy Local Chapter (2020-present)
- Co-founder of NEMB committee of American Society for Mechanical Engineers
- Over 5 patents in Nanomedicine
Dr. Decuzzi has secured over 15M€ in research funding from prestigious sources including NIH, DOD, CPRIT, ESF, and ERC. His laboratory at IIT Genova maintains active collaborations with international institutions and includes numerous postdoctoral researchers working across disciplines including molecular medicine, medicinal chemistry, and translational pharmacology. The lab's interdisciplinary approach bridges engineering principles with clinical applications to develop next-generation therapeutic delivery systems.
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