Pablo Tamayo

Dr. Pablo Tamayo is a Professor in the Department of Medicine at the University of California San Diego School of Medicine. His research focuses on cancer genomics, molecular oncology, and computational biology. He leads NIH-funded projects including the GenePattern platform for integrative omics analysis and studies on synthetic lethal gene interactions in cancer. His work spans pancreatic cancer metastasis, HPV-driven oncogenesis, and immunotherapy response mechanisms.

• Role: Principal Investigator/Co-PI in multiple NIH grants (U24CA248457, U01CA217885, etc.)
• Key Research: Cancer genomics, tumor microenvironment, computational tools for omics analysis

His lab investigates transcriptional regulation, cellular reprogramming, and synthetic lethality networks. Recent studies include YAP-driven stem cell reprogramming in oral cancers and MICAL2's role in pancreatic metastasis. He collaborates widely with institutions like UCSD's Altman Clinical and Translational Research Institute and has published over 100 peer-reviewed articles.

Publications highlight translational research in immunotherapy combinations, drug resistance mechanisms, and molecular biomarkers for personalized medicine.