Owen Rackham

Dr. Owen Rackham is an Associate Professor in Systems Biology at the University of Southampton, jointly appointed since 2020. He holds a PhD in Complexity Sciences and previously served as an MRC Career Development Fellow at Imperial College London (2012–2015) and Senior Research Fellow at Duke-NUS Medical School (2015–2016). He co-founded Mogrify Ltd., a cell therapy spin-out company commercializing his computational tools for cell reprogramming.

His research focuses on integrating computational approaches with experimental biology to understand cellular reprogramming and disease mechanisms. Key areas include:

• Cell fate control via computational modeling
• High-throughput sequencing analysis
• Data-driven drug discovery

Current projects involve:

• AI-driven cell-type expansion (BBSRC-funded)
• Epigenetic mechanisms in early-life adversity
• Multidisciplinary spatial biology platforms

He leads the Cell and Molecular Medicine theme at the Alan Turing Institute and has published extensively in top journals like Nature and Nature Machine Intelligence. His work has led to patent applications and licensing partnerships.