About
Owen N. Witte is a Professor at the David Geffen School of Medicine, University of California Los Angeles (UCLA), with dual appointments in Microbiology, Immunology & Molecular Genetics and Molecular and Medical Pharmacology. His research focuses on prostate cancer, neuroendocrine cancer, T cell receptor engineering, and molecular pharmacology.
Research Highlights:
- Identified PGC-1α's role in neuroendocrine cancer progression
- Developed nanovial-based TCR screening for cancer immunopeptidomics
- Explored MYC-dependent RNA splicing in prostate cancer
- Mapped genomic/epigenomic landscapes of aggressive prostate cancer
Scientific Awards:
- NIH U01CA233074
- NIH R01CA222877
- NIH R01CA220238
- NIH U01CA164188
Collaborative Work includes immunotherapy development, cancer stem cell characterization, and precision medicine strategies for lethal neuroendocrine prostate cancer.
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