About
Dr. Ole Isacson is a Professor of Neurology (Neuroscience) at Harvard Medical School and Professor of Neurology at Massachusetts General Hospital. As founding Director of the Neuroregeneration Research Institute (NRI) at McLean Hospital, he leads pioneering work in regenerative therapies for brain disorders. His research has been continuously funded by NIH, DOD, and private foundations since establishing his laboratory at Harvard.
He holds a Medical Bachelor and Doctor of Medicine (Neurobiology) from Lund University (1987), followed by postdoctoral training at the University of Cambridge.
Research Focus: Isacson's work centers on reversing neurodegenerative pathologies through innovative approaches. Key areas include:
- Stem cell-derived neuron transplantation for Parkinson's and Huntington's disease
- Molecular profiling of vulnerable neurons for neuroprotection
- Axon/synapse regeneration techniques
- Genetic engineering and neural cell sorting methodologies
Honors:
- Fellow of AAAS (2014)
- NIH Udall Center of Excellence Award
Leadership & Impact: He has trained researchers through NIH-funded programs, advised regulatory agencies (FDA, NIH, DOD), and co-founded biotech startups. The NRI has enabled clinical trials for Parkinson's and Huntington's disease based on his discoveries.
