Nynke Dekker

Professor Nynke Dekker leads the Nynke Dekker Lab at the Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology. Her research focuses on unraveling the dynamics of DNA and RNA replication through single-molecule biophysics and advanced biochemical approaches. The lab will relocate to the University of Oxford in summer 2024.

• BSc (Physics & Applied Mathematics) - Yale University
• MSc (Physics) - Leiden University
• PhD (Physics) - Harvard University

Using state-of-the-art single-molecule fluorescence and force spectroscopy techniques, her lab investigates:

• Real-time tracking of replication machinery
• Interactions in eukaryotic, bacterial, and viral systems
• Chromatin and epigenetic replication dynamics
• Biomedical applications of replication studies
• Drug-induced mutation mechanisms
• Physiological condition monitoring

The lab's publications highlight technological innovations (e.g., integrated force-fluorescence microscopy) and mechanistic studies of replication processes, with applications in both fundamental biology and biomedical research.