About
Dr. Nicole Prior is a Lecturer in Stem Cell Biology at the University of Southampton's Department of Biological Sciences. She serves as Principal Investigator for liver development and regeneration research using 3D organoid systems. Her work spans three key research groups: the Precision Biosciences Innovation Hub, Cell and Developmental Biology, and the Centre for Human Development, Stem Cells and Regeneration.
Her research focuses on:
- Genomic and metabolic networks in liver progenitor differentiation
- 3D organoid culture systems for developmental modeling
- Metabolic signaling in embryonic and adult liver homeostasis
- Translational applications for liver disease therapies
Current projects include:
- Chemically defined biomimetic hydrogels for organoid cultures
- Metabolic regulation of hepatocyte differentiation
- Non-alcoholic fatty liver disease progression analysis
- Molecular phenotyping using multi-parameter flow cytometry
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