Neil L. Kelleher

Neil L. Kelleher is the Walter and Mary E. Glass Professor of Molecular Biosciences at Weinberg College of Arts and Sciences and Professor of Medicine (Hematology & Oncology) at Feinberg School of Medicine, Northwestern University. He also serves as Director of the Chemistry of Life Processes Institute and Northwestern Proteomics.

His research focuses on top-down proteomics, chromatin biology, and natural product discovery. He leads the global Human Proteoform Project (HPfP) to map 250,000 human proteoforms across 4,000 cell types. His lab developed the ProSight software suite, used by over 1,000 labs worldwide.

His publications span computational proteomics, cancer epigenetics, and mass spectrometry applications. Recent articles address automated top-down proteomics, histone methylation dynamics, and non-ribosomal peptide synthesis in Molecular Biosystems, Journal of Biological Chemistry, and Chemistry & Biology.

• Biemann Medal (2009)
• Pittsburgh Conference Achievement Award (2008)
• Pfizer Award in Enzyme Chemistry (2006)
• Presidential Early Career Award for Scientists and Engineers (2005)

Kelleher has mentored ~50 Ph.D. students and postdocs. He co-founded startups like Nativetdms.org and IntegratedProteinTechnologies.com. His lab combines Fourier-Transform Mass Spectrometry with intact protein analysis to study proteoforms and their role in disease.