About
Neil Billington is an Assistant Professor at the West Virginia University School of Medicine, Department of Biochemistry and Molecular Medicine. His research focuses on the biophysical and molecular mechanisms of motor proteins like myosin and kinesin, particularly their roles in cytoskeletal dynamics, ciliopathies, and human diseases.
Research Interests
Billington's work explores:
- Regulation of unconventional myosins (Myosin-7a, Myosin-5) and their roles in cellular cargo transport
- Structural and functional dynamics of kinesin-2 in ciliopathies
- Tension formation and mechanical adaptation in nonmuscle myosin filaments
- Protein interactions governing stereocilia and centrosome motility
- Therapeutic strategies for retinal and neurological disorders
Recent Publications
His recent publications highlight advances in understanding motor protein mechanics, including single-molecule analyses of kinesin-2 in ciliopathies, regulatory mechanisms of myosin-7a in actin bundle assembly, and novel insights into nonmuscle myosin tension formation. He also investigates the therapeutic potential of archaeal proteasomes in retinal diseases and the role of TUBB4B in cochlear development.
Scientific Awards
No awards or honors were mentioned in the provided data.
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