Natalie Linea Hauglund

Natalie Linea Hauglund is a Researcher at the Center for Translational Neuromedicine within the Faculty of Health and Medical Sciences at the University of Copenhagen. Her research focuses on the glymphatic system, sleep physiology, and advanced brain imaging techniques, contributing significantly to our understanding of brain clearance mechanisms.

Her primary research interests include:

• Neuroscience and the glymphatic system
• Sleep physiology and its impact on brain clearance mechanisms
• Brain imaging techniques for studying cerebrospinal fluid dynamics
• Neurovascular coupling and its role in brain health
• Development of novel methods for dynamic imaging of brain processes
• Relationship between neurotransmitters and brain clearance

Dr. Hauglund's groundbreaking work on norepinephrine-mediated slow vasomotion driving glymphatic clearance during sleep, published in Cell (2025), has reshaped understanding of sleep's critical role in brain health. Her research on the mesothelium dividing the subarachnoid space into functional compartments (Science, 2023) has provided fundamental insights into brain anatomy and fluid dynamics.

Her scientific contributions have received extensive recognition across multiple platforms, with coverage by hundreds of news outlets, references in numerous Wikipedia pages, mentions in patents, and widespread discussion on social media. Her publication on subarachnoid space compartmentalization has garnered 175 Scopus citations, reflecting its significant impact on the field.

Dr. Hauglund collaborates extensively with leading researchers including Maiken Nedergaard, whose laboratory has pioneered glymphatic system research. Her interdisciplinary approach combines neuroscience, physiology, and imaging techniques to advance understanding of brain function and clearance mechanisms, with potential applications for neurodegenerative diseases where waste clearance is impaired.