Nan Sethakorn

Nan Sethakorn, MD, PhD, is an Assistant Professor in the Department of Cancer Biology at Loyola University Chicago. His research focuses on lung cancer metastasis, particularly bone metastases and tumor microenvironment interactions. He develops patient-specific tumor-on-chip models and employs circulating tumor cell analysis for biomarker discovery. His work aims to identify mechanisms of treatment resistance and improve therapies for lung cancer.

Education:

• BS in Biological Sciences, University of Illinois Chicago
• MD/PhD in Cancer Biology, University of Chicago Pritzker School of Medicine
• Residency in Internal Medicine, University of Wisconsin Hospitals
• Fellowship in Medical Oncology, University of Wisconsin Hospitals

Research Interests:

• Non-small cell lung cancer
• Bone metastases and tumor microenvironment dynamics
• Resistance to targeted therapies
• 3D organoid models and microfluidic platforms

Publications Overview: His recent work emphasizes tumor-on-chip systems for drug testing, liquid biopsies for biomarker analysis, and immune profiling of bone metastasis microenvironments. Key contributions include studies on PD-L1 expression in circulating tumor cells and longitudinal profiling of renal cell carcinoma.

Lab/Teams: His lab integrates engineering and oncology to create innovative models for studying cancer-stromal interactions and drug response in metastatic settings.