
About
Ming Xiao serves as a Professor in Drexel University's School of Biomedical Engineering, Science and Health Systems, where he leads pioneering research in genomic technology development with significant applications in molecular diagnostics, cell/gene therapies, and cancer screening. His work has established critical methodologies for understanding human genome structures and variations through innovative single-molecule approaches.
His academic foundation includes:
- PhD in Biophysics from Baylor University (1997)
- BS in Biomedical Engineering from Huazhong University of Science and Technology (1988)
Dr. Xiao's research program integrates micro/nanotechnology, single-molecule detection, and CRISPR-based systems to advance genomic analysis. His laboratory specializes in developing optical mapping techniques and nanofluidic platforms that enable high-resolution genome characterization, with particular emphasis on telomere biology, structural variation detection, and haplotype determination. These technologies bridge engineering principles with clinical applications in cancer diagnostics and precision medicine.
Analysis of his publication history reveals a consistent trajectory from foundational single-molecule methods (2007-2012) toward sophisticated CRISPR-integrated genomic tools (2015-2024). Recent work demonstrates increasing focus on clinical translation, particularly in cancer genomics through telomere analysis and targeted resequencing strategies. His research consistently appears in high-impact journals including Nature Biotechnology, Nucleic Acids Research, and Genes, reflecting substantial contributions to both methodological innovation and biological discovery.
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