Michael Plevin

Dr. Michael Plevin is a Senior Lecturer in Molecular Biophysics and Royal Society Industry Fellow at the University of York's Department of Biology. His research focuses on biomolecular recognition mechanisms, protein engineering for industrial applications, and liquid-liquid phase separation. He employs structural biology tools like X-ray crystallography, cryoEM, and NMR spectroscopy. Current collaborations include Eluceda Ltd, Syngenta, and Oxford Nanopore Technologies. Dr. Plevin also explores aromatic interactions in proteins and promotes positive research culture through initiatives like the Enhancing Research Culture working group.

His teaching emphasizes biophysical techniques and protein engineering, including modules on biomacromolecule structure determination. He supervises PhD students in protein engineering, molecular recognition, and sequence-structure-function relationships. Dr. Plevin has held grants from UKRI, The Royal Society, and industry partners. His work bridges academic and industrial challenges, with projects on non-antibody scaffolds, DNA helicases, and nanopores.

Key research themes include phase separation dynamics in cellular organization, weak transient interactions, and Rubisco's role in algal photosynthesis. He collaborates with experts in algal biology and single-molecule biophysics. His contributions to isotopic labeling methods for NMR have advanced structural studies of large proteins.