Michael Inouye

Professor Michael Inouye is a leading systems genomics and population health researcher at the University of Cambridge (Department of Public Health and Primary Care) and Baker Heart & Diabetes Institute (Melbourne). His work bridges statistical genetics, computational biology, and clinical translation, with a focus on cardiovascular/respiratory diseases and sustainable research practices.

• Director of Research (Research Professor) since 2021
• Honorary Professorial Fellow at University of Melbourne since 2021
• Co-leader of Cambridge Baker Systems Genomics Initiative since 2017

Research Interests include:

• Polygenic risk score development and clinical implementation
• Multi-omic integration (genomics, proteomics, microbiomics)
• Host-microbiome interactions in disease
• Sustainable computational methodologies
• Cardiometabolic disease prevention

Scientific Contributions show leadership in:

• Developing the Polygenic Score Catalog infrastructure
• Creating environmentally sustainable algorithmic frameworks
• Elucidating microbiome contributions to chronic diseases
• Advancing multi-modal risk prediction models
• Integrating genetic and metabolic pathway analysis

Recent Publications demonstrate expertise across:

• Polygenic score optimization for blood traits and diabetes
• Microbiome-disease interaction networks
• Computational sustainability in biomedical research
• Cardiovascular risk stratification
• Multi-omic data harmonization
• Genetic determinants of molecular phenotypes