Michael Boemo

Dr Michael Boemo is an Assistant Professor at the University of Cambridge, holding dual appointments in the Department of Pathology and Department of Genetics. He leads research at the intersection of computational biology, DNA replication, and cancer genomics, developing machine learning tools to analyze replication stress and genomic instability.

• Academic Background: BA in Mathematics (Rutgers University), PhD in Physics (University of Oxford)
• Research Focus: Genomic instability in cancer, DNA replication/repair defects, computational modeling using machine learning and high-performance simulations
• Teaching: Lectures in Natural Sciences Tripos (mathematical biology, genetics, systems biology), module organizer for cancer biology and biological modeling

His research group leverages nanopore sequencing and AI to map replication fork dynamics, revealing how stalled forks generate mutations in cancer cells and pathogens. Recent work examines extrachromosomal DNA replication vulnerabilities and transcription-replication conflicts.

Dr Boemo collaborates across computational biology and cancer research domains, with publications spanning journals like Nature Methods, Cell, and PLoS Computational Biology. His lab develops tools such as DNAscent for replication fork analysis and explores therapeutic targeting of replication stress.