Melanie Majure

Melanie Majure, MD is an Associate Professor in the Department of Medicine at the University of California, San Francisco (UCSF) School of Medicine. Her clinical and research work focuses on breast oncology, particularly metastatic disease, immune-related toxicities, and fertility preservation.

Education:

• BS in Neuroscience, Davidson College (2000)
• MD, Stanford University School of Medicine (2009)
• Internal Medicine Residency, Stanford University Hospital (2012)
• Hematology/Oncology Fellowship, UCSF (2015)

Her research interests center on improving outcomes in breast cancer through clinical trials, toxicity management, and patient-centered care. She investigates immune-related adverse events (irAEs), neutropenia with novel agents, leptomeningeal disease, and psychosocial aspects such as fertility preservation and child-bearing attitudes in young patients. She is deeply involved in multi-institutional studies and real-world evidence research.

Recent publications show a strong trend in immune checkpoint inhibitor toxicities, metastatic complications (brain and leptomeningeal metastases), and treatment optimization in advanced breast cancer. Her work spans clinical trials, retrospective cohort studies, and biomarker validation using NGS and liquid biopsies.

Scientific Contributions:

• Extensive publications in high-impact journals including Clinical Cancer Research, JAMA Oncology, and Breast Cancer Research and Treatment
• Active participant in the I-SPY2 trial and other phase I/II studies
• Focus on palliative care integration in metastatic breast cancer

She collaborates closely with leading UCSF oncologists including Michelle Melisko, Hope Rugo, and Laura Esserman. She has no listed students or awards in the provided text, but her research program is robust and clinically impactful. She is affiliated with clinical trials and academic senate committee service at UCSF.