Mehreen Datoo

Mehreen Datoo is a Clinical Research Fellow and DPhil Student at the Nuffield Department of Medicine, University of Oxford, specializing in the Malaria Programme's Pre-erythrocytic Vaccines research group. Her work focuses on advancing malaria vaccine candidates through clinical evaluation and public health impact assessment.

Her research interests include:

• Malaria vaccinology and pre-erythrocytic stage targeting
• Phase 3 clinical trial design for vaccine efficacy/safety
• Mathematical modeling of vaccine cost-effectiveness
• Immunogenicity profiling across diverse populations
• Public health implementation strategies
• Cross-disease vaccine platform development

Analysis of her recent publications reveals concentrated expertise in the R21/Matrix-M malaria vaccine, with pivotal contributions to African pediatric trials, cost-effectiveness modeling, and safety monitoring. Her work bridges clinical research with real-world policy applications, demonstrating significant potential for malaria burden reduction. Earlier research on Ebola virus prime-boost regimens establishes her broader capability in infectious disease vaccinology.

Dr. Datoo operates within Oxford's Nuffield Department of Medicine Malaria Programme, leveraging institutional resources for high-impact translational research in global vaccine development.