
About
Maxim Prigozhin is an Assistant Professor at Harvard University, holding dual appointments in the Department of Molecular and Cellular Biology and the Department of Applied Physics. His research focuses on single-cell and single-molecule biophysics, particularly studying transmembrane signaling via G-protein-coupled receptors and developing advanced microscopy techniques like time-resolved cryo-vitrification. The Prigozhin lab integrates experimental and computational approaches, including stochastic modeling and statistical analysis, to explore protein folding dynamics and biophysical interactions.
Located in Harvard's SEAS and MCB departments, the lab emphasizes cross-disciplinary work at the interface of nanotechnology, cell biology, and biophysics. Recent advancements include cathodoluminescent nanoprobes for electron microscopy and pressure-jump simulations of protein dehydration-folding dynamics. Their methodologies bridge molecular-level insights with macroscopic biological processes.
Advising and grants: While specific grant details are not provided, the lab's 2019 establishment and student fellowship awards highlight active research funding and mentorship in biophysics and applied physics. The lab's Values Statement underscores ethical and collaborative scientific practices.
Key technical innovations include gold nanorod-biology interfaces and PEGylation strategies for enhancing protein stability. These efforts aim to advance both fundamental biophysical understanding and translational applications in microscopy and drug delivery.
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